Dear Colleagues, We are happy to welcome you at the first EACSGE (Esophageal Adenocarcinoma Study Group Europe) Symposium that will be held on February 13-14th 2020, at the Royal Hotel Carlton in Bologna, Italy. The EACSGE is a joined effort of the Universities of Bologna, Genova, Helsinki, of the Amsterdam University Medical Centers, and the National Oncologic IRST/IRCCS (Scientific Institute for Treatment and Research) of Meldola Italy; the EACSGE has been recently established to address the rising problem of a highly malignant disease which we believe can only be dealt with through implementation of novel state-of-the-art translational and fundamental research. Esophageal adenocarcinoma indeed requires innovative approaches, to prevent its further increase and to improve patient outcomes. The EACSGE believes that this can be achieved only through bringing together all experts in the field of esophageal adenocarcinoma and to initiate effective collaborations. These collaborative efforts will aim at bringing experts from different disciplines together to develop and implement efficient screening and surveillance programs, and to apply urgently required innovative combinatorial treatment strategies. The recent insights in the biological make up of esophageal adenocarcinoma and its precursor lesion, Barrett’s esophagus, offers unique possibilities to achieve such goals. Therefore, the field of translational research on esophageal diseases is expanding and holds great promise for improving therapy and patient management. This first EACSGE symposium will have a clear focus on the outcomes of disease biology and evolution; in addition, innovative study protocols, translational and early clinical studies on esophageal adenocarcinoma and Barrett’s esophagus will be presented. The discussion among eminent biologists, oncologists, pathologists, gastroenterologists and surgeons, will produce research programs aimed to identify new therapeutic strategies based on the identification of case by case biological patterns by means of bio-molecular prognostic and progression markers. This multi-disciplinary meeting is offered to clinician and scientists in the field of genomic medicine, pathology, gastroenterology, oncology and surgery with special interest in esophageal diseases. We invite you to submit your work as abstracts that will be selected for oral presentation or for the posters session. Information on abstract submission and deadline will be available soon on the website of the Organizing Secretariat of the meeting.